Barbara Bain won the Primetime Emmy Awards for Outstanding Lead Actress in a Drama Series three times (1967, 1968, 1969).
| Year | Contest | Category | For | Sources |
|---|---|---|---|---|
| 1969 | Primetime Emmy Awards | Outstanding Lead Actress in a Drama Series | Mission: Impossible | 1 · 2 |
| 1968 | Primetime Emmy Awards | Outstanding Lead Actress in a Drama Series | Mission: Impossible | 1 · 2 |
| 1967 | Primetime Emmy Awards | Outstanding Lead Actress in a Drama Series | Mission: Impossible | 1 · 2 |