Felicity Huffman won the Primetime Emmy Awards for Outstanding Lead Actress in a Comedy Series in 2005 for Desperate Housewives. Felicity Huffman won the Golden Globe Awards for Best Actress in a Motion Picture – Drama in 2006 for Transamerica.
| Year | Contest | Category | For | Sources |
|---|---|---|---|---|
| 2006 | Golden Globe Awards | Best Actress in a Motion Picture – Drama | Transamerica | 1 · 2 |
| 2005 | Primetime Emmy Awards | Outstanding Lead Actress in a Comedy Series | Desperate Housewives | 1 · 2 |