Kelsey Grammer won the Primetime Emmy Awards for Outstanding Lead Actor in a Comedy Series 4 times (1994, 1995, 1998, 2004).
| Year | Contest | Category | For | Sources |
|---|---|---|---|---|
| 2004 | Primetime Emmy Awards | Outstanding Lead Actor in a Comedy Series | Frasier | 1 · 2 |
| 1998 | Primetime Emmy Awards | Outstanding Lead Actor in a Comedy Series | Frasier | 1 · 2 |
| 1995 | Primetime Emmy Awards | Outstanding Lead Actor in a Comedy Series | Frasier | 1 · 2 |
| 1994 | Primetime Emmy Awards | Outstanding Lead Actor in a Comedy Series | Frasier | 1 · 2 |