Mary Tyler Moore won the Primetime Emmy Awards for Outstanding Lead Actress in a Comedy Series 4 times (1966, 1973, 1974, 1976).
| Year | Contest | Category | For | Sources |
|---|---|---|---|---|
| 1976 | Primetime Emmy Awards | Outstanding Lead Actress in a Comedy Series | The Mary Tyler Moore Show | 1 · 2 |
| 1974 | Primetime Emmy Awards | Outstanding Lead Actress in a Comedy Series | The Mary Tyler Moore Show | 1 · 2 |
| 1973 | Primetime Emmy Awards | Outstanding Lead Actress in a Comedy Series | The Mary Tyler Moore Show | 1 · 2 |
| 1966 | Primetime Emmy Awards | Outstanding Lead Actress in a Comedy Series | The Dick Van Dyke Show | 1 · 2 |