Tony Shalhoub won the Primetime Emmy Awards for Outstanding Lead Actor in a Comedy Series three times (2003, 2005, 2006).
| Year | Contest | Category | For | Sources |
|---|---|---|---|---|
| 2006 | Primetime Emmy Awards | Outstanding Lead Actor in a Comedy Series | Monk | 1 · 2 |
| 2005 | Primetime Emmy Awards | Outstanding Lead Actor in a Comedy Series | Monk | 1 · 2 |
| 2003 | Primetime Emmy Awards | Outstanding Lead Actor in a Comedy Series | Monk | 1 · 2 |